Package: twosigma Type: Package Title: DE Analysis for Single-Cell RNA-Sequencing Data Version: 1.0.2 Date: 2021-12-10 Authors@R: c(person("Eric", "Van Buren", email = "edvanburen@gmail.com", role = c("aut", "cre")),person("Yun", "Li",role="aut"),person("Di", "Wu",role="aut"),person("Ming", "Hu",role="aut")) Maintainer: Eric Van Buren Description: Implements the TWO-Component Single Cell Model-Based Association Method (TWO-SIGMA) for gene-level differential expression (DE) analysis and DE-based gene set testing of single-cell RNA-sequencing datasets. See Van Buren et al. (2020) and Van Buren et al. (2021) . License: AGPL-3 Imports: multcomp (>= 1.4-13), glmmTMB, methods, pscl (>= 1.5.5), pbapply (>= 1.4.0), parallel (>= 3.6.3), doParallel (>= 1.0.15) Encoding: UTF-8 URL: https://github.com/edvanburen/twosigma BugReports: https://github.com/edvanburen/twosigma/issues RoxygenNote: 7.1.0 Suggests: testthat Config/pak/sysreqs: cmake make libicu-dev Repository: https://edvanburen.r-universe.dev Date/Publication: 2023-06-08 19:19:02 UTC RemoteUrl: https://github.com/edvanburen/twosigma RemoteRef: HEAD RemoteSha: 14b8f3edf9ab8dc5a23073808f50f36ca211bed8 NeedsCompilation: no Packaged: 2026-09-23 07:03:48 UTC; root Author: Eric Van Buren [aut, cre], Yun Li [aut], Di Wu [aut], Ming Hu [aut]