Package: twosigma 1.0.2

twosigma: DE Analysis for Single-Cell RNA-Sequencing Data

Implements the TWO-Component Single Cell Model-Based Association Method (TWO-SIGMA) for gene-level differential expression (DE) analysis and DE-based gene set testing of single-cell RNA-sequencing datasets. See Van Buren et al. (2020) <doi:10.1002/gepi.22361> and Van Buren et al. (2021) <doi:10.1101/2021.01.24.427979>.

Authors:Eric Van Buren [aut, cre], Yun Li [aut], Di Wu [aut], Ming Hu [aut]

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Bug tracker:https://github.com/edvanburen/twosigma/issues

On CRAN:

8 exports 8 stars 1.33 score 26 dependencies 3 scripts 240 downloads

Last updated 1 years agofrom:14b8f3edf9. Checks:OK: 3 NOTE: 4. Indexed: yes.

Exports:adhoc.twosigmalr.twosigmalr.twosigma_customsimulate_zero_inflated_nb_random_effect_datatest.vc.twosigmatwosigmatwosigma_customtwosigmag

Dependencies:bootcodetoolsdoParallelforeachglmmTMBiteratorslatticelme4MASSMatrixmgcvminqamultcompmvtnormnlmenloptrnumDerivpbapplypsclRcppRcppEigensandwichsurvivalTH.dataTMBzoo