Package: twosigma 1.0.2

twosigma: DE Analysis for Single-Cell RNA-Sequencing Data

Implements the TWO-Component Single Cell Model-Based Association Method (TWO-SIGMA) for gene-level differential expression (DE) analysis and DE-based gene set testing of single-cell RNA-sequencing datasets. See Van Buren et al. (2020) <doi:10.1002/gepi.22361> and Van Buren et al. (2021) <doi:10.1101/2021.01.24.427979>.

Authors:Eric Van Buren [aut, cre], Yun Li [aut], Di Wu [aut], Ming Hu [aut]

twosigma_1.0.2.tar.gz
twosigma_1.0.2.zip(r-4.7)twosigma_1.0.2.zip(r-4.6)twosigma_1.0.2.zip(r-4.5)
twosigma_1.0.2.tgz(r-4.6-any)twosigma_1.0.2.tgz(r-4.5-any)
twosigma_1.0.2.tar.gz(r-4.7-any)twosigma_1.0.2.tar.gz(r-4.6-any)
twosigma_1.0.2.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
card.svg |card.png
twosigma/json (API)
NEWS

# Install 'twosigma' in R:
install.packages('twosigma', repos = c('https://edvanburen.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/edvanburen/twosigma/issues

On CRAN:

Conda:

3.60 score 8 stars 3 scripts 212 downloads 8 exports 74 dependencies

Last updated from:14b8f3edf9. Checks:7 NOTE, 2 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-x86_64NOTE206
source / vignettesOK191
linux-release-x86_64NOTE133
macos-release-arm64NOTE209
macos-oldrel-arm64NOTE170
windows-develNOTE128
windows-releaseNOTE122
windows-oldrelNOTE102
wasm-releaseOK124

Exports:adhoc.twosigmalr.twosigmalr.twosigma_customsimulate_zero_inflated_nb_random_effect_datatest.vc.twosigmatwosigmatwosigma_customtwosigmag

Dependencies:backportsbootbroomclicodetoolscolorspacecowplotcpp11DerivdoBydoParalleldplyrfarverforeachforecastfracdiffgenericsggplot2glmmTMBgluegtableisobanditeratorslabelinglatticelifecyclelme4lmtestmagrittrMASSMatrixmgcvmicrobenchmarkminqamodelrmultcompmvtnormnlmenloptrnnetnumDerivpbapplypbkrtestpillarpkgconfigpsclpurrrR6rbibutilsRColorBrewerRcppRcppArmadilloRcppEigenRdpackreformulasrlangS7sandwichscalesstringistringrsurvivalTH.datatibbletidyrtidyselecttimeDateTMBurcautf8vctrsviridisLitewithrzoo